产品详情
产品名称Met Antibody
来源种属Rabbit
克隆性Polyclonal
纯化Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide.
应用WB
种属反应性Human;Mouse;Rat
特异性The antibody detects endogenous level of total Met protein.
免疫原类型Peptide-KLH
免疫原描述Peptide sequence around aa.1232~1236 (K-E-Y-Y-S) derived from Human Met.
基因/蛋白名称Met
标记Unconjugated
别名HGF receptor; HGF-SF receptor; Met proto-oncogene tyrosine kinase; c-met; kinase Met
数据库入口号Swiss-Prot: P08581
NCBI Protein: NP_000236.2
Uniprot
P08581
浓度1.0mg/ml
配方Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
保存Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.
应用详情
Predicted MW: 156kd
Western blotting: 1:500~1:1000
Western blot analysis of extracts from HepG2 cells using Met(Ab-1234) Antibody #21220 and the same antibody preincubated with blocking peptide.
Receptor for hepatocyte growth factor and scatter factor. Has a tyrosine-protein kinase activity. Functions in cell proliferation, scattering, morphogenesis and survival.
Gherardi E. et al. (2003).Proc Natl Acad Sci U S A. 100(21): 12039-12044.
Shiu SH. et al. (2001) Proc Natl Acad Sci U S A. 98(19): 10763-10768.
Hughes AL. et al. (2001) Genome Res. 11(5): 771-780.
Onuchic LF. et al. (2002) Am J Hum Genet. 70(5): 1305-1317.
如果您使用该产品21220发表了文章，请通知我们，让我们可以引用您的文献。
et al,MicroRNA-449a Is Downregulated in Non-Small Cell Lung Cancer and Inhibits Migration and Invasion by Targeting c-Met.
, (2013),
PMID:
23734217
et al,miR-34a inhibits migration and invasion by down-regulation of c-Met expression in human hepatocellular carcinoma cells.
, (2008),
PMID:
19006648
et al,miR-34a Inhibits Migration and Invasion by Down-Regulation of c-Met Expression in Human Hepatocellular Carcinoma Cells.In Cancer Lett on 2009 Mar 8 by Na Li, Hanjiang Fu,et al..PMID:19006648
, (2009),
PMID:
19006648
et al,MicroRNA-449a is downregulated in non-small cell lung cancer and inhibits migration and invasion by targeting c-Met. In PLoS One on 2013 May 29 by Wenting Luo,
Bo Huang, et al..PMID: 23734217
, (2013),
PMID:
23734217
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