产品详情
产品名称MTMR3 Polyclonal Antibody
来源种属Rabbit
克隆性Polyclonal
亚型IgG
纯化Affinity purification
应用WB,IF
种属反应性Human;Mouse
免疫原描述Recombinant fusion protein of human MTMR3 (NP_066576.1).
标记Unconjugated
别名MTMR3; FYVE-DSP1; ZFYVE10; myotubularin-related protein 3
数据库入口号Swiss-Prot#:Q13615
NCBI Gene ID:8897
Uniprot
Q13615
计算分子量134kDa
配方Avoid freeze / thaw cycles.|Buffer: PBS with 50% glycerol, pH7.4.
保存Store at -20˚C
应用详情
WB 1:500 - 1:2000
IF 1:50 - 1:100
Western blot analysis of extracts of various cell lines, using MTMR3 antibody.
This gene encodes a member of the myotubularin dual specificity protein phosphatase gene family. The encoded protein is structurally similar to myotubularin but in addition contains a FYVE domain and an N-terminal PH-GRAM domain. The protein can self-associate and also form heteromers with another myotubularin related protein. The protein binds to phosphoinositide lipids through the PH-GRAM domain, and can hydrolyze phosphatidylinositol(3)-phosphate and phosphatidylinositol(3,5)-biphosphate in vitro. The encoded protein has been observed to have a perinuclear, possibly membrane-bound, distribution in cells, but it has also been found free in the cytoplasm. Multiple transcript variants encoding different isoforms have been found for this gene.
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