产品详情
产品名称TFR2 Polyclonal Antibody
来源种属Rabbit
克隆性Polyclonal
亚型IgG
纯化Affinity purification
应用WB,IHC,IF
种属反应性Human;Mouse
免疫原描述Recombinant fusion protein of human TFR2 (NP_003218.2).
标记Unconjugated
别名TFR2;HFE3;TFRC2
数据库入口号Uniprot:Q9UP52
GeneID:7036
Uniprot
Q9UP52
Gene ID
7036
计算分子量89kDa
实际分子量100KDa
配方PBS with 0.02% sodium azide,50% glycerol,pH7.3.
保存Store at -20˚C. Avoid freeze / thaw cycles.
应用详情
WB 1:500 - 1:2000
IHC 1:50 - 1:200
IF 1:50 - 1:200
Western blot analysis of extracts of various cell lines, using TFR2 antibody.
Immunohistochemistry of paraffin-embedded human liver cancer using TFR2 antibody.
Immunofluorescence analysis of HepG2 cells using TFR2 Rabbit pAb.
This gene encodes a single-pass type II membrane protein, which is a member of the transferrin receptor-like family. This protein mediates cellular uptake of transferrin-bound iron, and may be involved in iron metabolism, hepatocyte function and erythrocyte differentiation. Mutations in this gene have been associated with hereditary hemochromatosis type III. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.
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et al,HUWE1 in Skeletal Muscle Prevents Muscle Fatigue via Maintaining Iron and Calcium Homeostasis
, (2025),
PMID:
41261985
Yes
