产品详情
产品名称TMEM30B Antibody
来源种属Rabbit
克隆性Polyclonal
纯化The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
应用WB
种属反应性Human
特异性The antibody detects endogenous levels of total TMEM30B protein.
免疫原类型Peptide
免疫原描述Synthesized peptide derived from internal of human TMEM30B.
基因/蛋白名称TMEM30B
标记Unconjugated
别名Cell cycle control protein 50B; Transmembrane protein 30B; TMEM30B; CDC50B; CC50B
数据库入口号Swiss-Prot: Q3MIR4
NCBI Gene ID: 161291
Uniprot
Q3MIR4
实际分子量38kd
浓度1.0mg/ml
配方Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
保存Store at -20˚C
应用详情
Western blotting: 1:500~1:3000
Western blot analysis of extracts from K562 cells, using TMEM30B antibody #34185.
Accessory component of a P4-ATPase flippase complex which catalyzes the hydrolysis of ATP coupled to the transport of aminophospholipids from the outer to the inner leaflet of various membranes and ensures the maintenance of asymmetric distribution of phospholipids. Phospholipid translocation seems also to be implicated in vesicle formation and in uptake of lipid signaling molecules. The beta subunit may assist in binding of the phospholipid substrate Probable. Can mediate the export of alpha subunits ATP8A1, ATP8B1, ATP8B2 and ATP8B4 from the ER to the plasma membrane.
The MGC Project Team, Genome Res. 14:2121-2127(2004).
Katoh Y., Oncol. Rep. 12:939-943(2004).
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