产品详情
产品名称ANXA8 Antibody
来源种属Rabbit
克隆性Polyclonal
纯化Antigen affinity purification.
应用WB IHC
种属反应性Human
特异性The antibody detects endogenous levels of total ANXA8 protein.
免疫原类型Recombinant Protein
免疫原描述Fusion protein corresponding to a region derived from internal residues of human annexin A8
基因/蛋白名称ANXA8
标记Unconjugated
别名ANX8
数据库入口号Swiss-Prot#: P13928
NCBI Gene ID: 653145
Gene Accssion: BC073755
Uniprot
P13928
实际分子量37kd
浓度1.3mg/ml
配方Rabbit IgG in pH7.3 PBS, 0.05% NaN3, 50% Glycerol.
保存Store at -20˚C
应用详情
Western blotting: 1:200-1:1000
Immunohistochemistry: 1:50-1:100
Gel: 10%SDS-PAGE
Lysate: 40ug A549 cell
Primary antibody: 1/300 dilution
Secondary antibody dilution: 1/8000
Exposure time: 2 minutes
Immunohistochemical analysis of paraffin-embedded Human esophagus cancer tissue using #35621 at dilution 1/35.
This gene encodes a member of the annexin family of evolutionarily conserved Ca2+ and phospholipid binding proteins. The encoded protein may function as an an anticoagulant that indirectly inhibits the thromboplastin-specific complex. Overexpression of this gene has been associated with acute myelocytic leukemia. A highly similar duplicated copy of this gene is found in close proximity on the long arm of chromosome 10.
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et al,Discovery of a Novel 1,4-Benzodiazepine Derivative as a Highly Selective ANXA3 Degrader for the Treatment of Triple-Negative Breast Cancer.
, (2025),
PMID:
40013713
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