产品详情
产品名称ADAM11 Antibody
来源种属Rabbit
克隆性Polyclonal
纯化Antigen affinity purification.
应用WB IHC
种属反应性Human;Mouse
特异性The antibody detects endogenous levels of total ADAM11 protein.
免疫原类型Peptide
免疫原描述Synthetic peptide corresponding to a region derived from internal residues of human ADAM metallopeptidase domain 11
基因/蛋白名称ADAM11
标记Unconjugated
别名MDC
数据库入口号Swiss-Prot#: O75078
NCBI Gene ID: 4185
Gene Accssion: NP_002381
Uniprot
O75078
实际分子量83kd
浓度1.5mg/ml
配方Rabbit IgG in pH7.3 PBS, 0.05% NaN3, 50% Glycerol.
保存Store at -20˚C
应用详情
Western blotting: 1:200-1:1000
Immunohistochemistry: 1:50-1:200
Gel: 10%SDS-PAGE
Lysates (from left to right): Hela and SKOV3 cell
Amount of lysate: 50ug per lane
Primary antibody: 1/500 dilution
Secondary antibody dilution: 1/8000
Exposure time: 10 minutes
Immunohistochemical analysis of paraffin-embedded Human lung cancer tissue using #37308 at dilution 1/40.
This gene encodes a member of the ADAM (a disintegrin and metalloprotease) protein family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. This gene represents a candidate tumor supressor gene for human breast cancer based on its location within a minimal region of chromosome 17q21 previously defined by tumor deletion mapping.
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