产品详情
产品名称GEMIN2 antibody
来源种属Rabbit
克隆性Polyclonal
亚型IgG
纯化Affinity purification
应用WB,IHC
种属反应性Human;Mouse;Rat
特异性The antibody detects endogenous level of total GEMIN2 protein.
免疫原类型Peptide
免疫原描述A synthetic peptide of human Gemin 2
基因/蛋白名称GEMIN2
标记Unconjugated
别名GEMIN2;SIP1;SIP1-delta
数据库入口号Uniprot:O14893
GeneID:8487
Uniprot
O14893
Gene ID
8487
实际分子量35kDa
浓度1.0mg/ml
配方PBS with 0.02% sodium azide,50% glycerol,pH7.3.
保存Store at -20˚C. Avoid freeze / thaw cycles.
应用详情
WB 1:500 - 1:1000
IHC 1:50 - 1:200
Western blot analysis of extracts of Jurkat cells, using Gemin 2 antibody.
Immunohistochemistry of paraffin-embedded rat liver using Gemin 2 Antibody.
Immunohistochemistry of paraffin-embedded human lung cancer using Gemin 2 Antibody.
Immunohistochemistry of paraffin-embedded mouse testis using Gemin 2 Antibody.
This gene encodes one of the proteins found in the SMN complex, which consists of several gemin proteins and the protein known as the survival of motor neuron protein. The SMN complex is localized to a subnuclear compartment called gems (gemini of coiled bodies) and is required for assembly of spliceosomal snRNPs and for pre-mRNA splicing. This protein interacts directly with the survival of motor neuron protein and it is required for formation of the SMN complex. A knockout mouse targeting the mouse homolog of this gene exhibited disrupted snRNP assembly and motor neuron degeneration.
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