产品详情
产品名称BLM Antibody
来源种属Rabbit
克隆性Polyclonal
纯化Antigen affinity purification
应用IHC
种属反应性Human
特异性The antibody detects endogenous levels of total BLM protein.
免疫原类型peptide
免疫原描述Synthetic peptide of human BLM
基因/蛋白名称BLM
标记Unconjugated
别名BS; RECQ2; RECQL2; RECQL3
数据库入口号Swiss-Prot#: P54132
NCBI Gene ID: 641
Uniprot
P54132
浓度0.8mg/ml
配方Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
保存Store at -20˚C
应用详情
Immunohistochemistry: 1: 20-100
The image on the left is immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using BLM Antibody at dilution 1/35, on the right is treated with synthetic peptide. (Original magnification: x200)
The Bloom syndrome gene product is related to the RecQ subset of DExH box-containing DNA helicases and has both DNA-stimulated ATPase and ATP-dependent DNA helicase activities. Mutations causing Bloom syndrome delete or alter helicase motifs and may disable the 3'-5' helicase activity. The normal protein may act to suppress inappropriate recombination.
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